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Improper alignment of the upper and lower teeth (malocclusion) may also occur.

The symptoms of cri du chat syndrome vary from case to case.Symptoms vary greatly from case to case depending upon the exact size and location of the deleted genetic material.Common symptoms include a distinctive cry that resembles the mewing of a cat, characteristic facial features, slow growth, and microcephaly, a condition that indicates that head circumference is smaller than would be expected for an infant's age and sex.Affected children also exhibit delays in the acquisition of skills requiring the coordination of muscular and mental activities (psychomotor disability) and moderate to severe intellectual disability.Additional symptoms affecting different organ systems of the body can also occur.

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